The project described above is supported by Award Number 1AC2HL101489 from the National Heart, Lung, and Blood Institute of the National Institutes of Health. This award has been issued under the American Recovery and Reinvestment Act of 2009 for a 2-year period. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Heart, Lung, and Blood Institute or the National Institutes of Health.